Heyde syndrome is a rare condition that involves a combination of aortic stenosis and gastrointestinal bleeding caused by angiodysplasia (abnormal blood vessels in the gastrointestinal tract). The condition is named after Edward C. Heyde, the physician who first described the association between aortic stenosis and gastrointestinal bleeding in 1958.
The exact cause of Heyde syndrome is not well understood, but it appears to result from a complex interaction between genetic predisposition, localized inflammation, and mechanical stress on the blood vessels of the gastrointestinal tract.
Symptoms of Heyde syndrome include shortness of breath, chest pain, fatigue, and dizziness due to aortic stenosis, as well as chronic or acute gastrointestinal bleeding.
Treatment typically involves aortic valve replacement to relieve the symptoms of aortic stenosis, as well as endoscopic treatment of gastrointestinal angiodysplasia to minimize the risk of recurrent bleeding. In some cases, anticoagulation therapy may be prescribed to help prevent blood clots in the blood vessels of the gastrointestinal tract.
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